Assisted Hatching Billed With Embryo Biopsy
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Billing for Ultrasounds and Labs
When billing for ultrasounds and labs, is it necessary
Use of Code 99211 for a Monitoring Appointment
Is it appropriate to use code 99211 if a patient is scheduled for a monitoring visit
Appropriate Use of Modifier -25
Is Modifier -25 appropriate in the monitoring cycle when an ultrasoundCoding Corner








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Topic Resources
Fertility and Sterility On Air - Roundtable: In Vitro Gametogenesis
This week, we welcome Dr. Paula Amato and Professor Glenn Cohen to discuss the legal and ethical implications of in vitro gametogenesis (IVG). Listen to the EpisodeASRM Center for Policy and Leadership Releases Policy Report on Gestational Carrier Pregnancies
ASRM Center for Policy and Leadership released a report discussing gestational carrier policy in the U.S. discussing it's impact and how lawmakers should proceed going forward. View the Press ReleaseASRM PRIMED scholar Dr. Caiyun Liao Publishes Article on RRM in JAMA
A new Viewpoint warns about the growing politicization and promotion of “restorative reproductive medicine." View the Press ReleaseFertility and Sterility On Air - Roundtable: Egg Sharing
Experts debate the ethics of egg sharing and split cycles, exploring patient autonomy, informed consent, diversity, and equitable fertility care. Listen to the EpisodeAssisted reproduction with advancing paternal and maternal age: an Ethics Committee opinion (2025)
Explore ethical considerations in assisted reproduction for older parents, balancing reproductive autonomy with potential offspring well-being. View the Committee OpinionUS IVF usage increases in 2023, leads to over 95,000 babies born
SART releases 2023 IVF data during National Infertility Awareness Week, showing record births and rising demand for ART to support growing families. View the Press ReleaseCode O09.01 vs O09.811 for Pregnancy Patients
Is code O09.01 acceptable for all pregnancy patients, or for same-sex cases View the AnswerDisclosure of medical errors and untoward events involving gametes and embryos: an Ethics Committee opinion (2024)
Medical providers have an ethical duty to disclose clinically significant errors involving gametes and embryos. View the Committee OpinionUse of preimplantation genetic testing for monogenic adult-onset conditions: an Ethics Committee opinion (2024)
Preimplantation genetic testing for adult-onset monogenic diseases is ethically allowed when fully penetrant or conferring disease predisposition. View the Committee OpinionWhen to use code Z31.83
When a patient is completing an approved fertility cycle, is it necessary View the AnswerTimed Intercourse Cycle Codes
Is it appropriate to utilize codes N97.8 or View the AnswerBilling Physician vs Service Physician
What physician’s name must be on the treatment notes and who we are permitted to bill to insurance for: View the AnswerJournal Club Global: Falha de implantação: realidade ou ilusão estatística?
Fertility and Sterility Global Journal Club from Brazil View the VideoThe use of hormonal contraceptives in fertility treatments: a committee opinion (2024)
Hormonal contraception aids in the timing of ART cycles, reduce ovarian cysts at IVF cycle initiation, and optimize visualization before hysteroscopy. View the Committee OpinionFamily members as gamete donors or gestational carriers: an Ethics Committee opinion (2024)
The use of adult intrafamilial gamete donors and gestational surrogates is ethically acceptable when all participants are fully informed and counseled. View the Committee DocumentSemen analysis and thaw code
Can we use the semen analysis presence and motility (89300) code along with a reproductive tissue thaw code (89354) View the AnswerBilling for assisted hatching at biopsy and transfer
We would also like to know if you can bill assisted hatching with biopsy and then assisted hatching again during the transfer cycle. View the AnswerDiagnosis code for donation
What is the diagnosis code for an embryo donation versus egg donation? View the AnswerCoding for an endometrial biopsy/Mock cycle
We had patients request us to bill their insurance for the two monitoring visits and the Endo BX and change the diagnosis code to something that is payable. View the AnswerFinancial ‘‘risk-sharing’’ or refund programs in assisted reproduction: an Ethics Committee opinion (2023)
Financial ‘‘risk-sharing’’ fee structures in programs charge patients a higher initial fee but provide reduced fees for subsequent cycles. View the Committee DocumentPrevention of moderate and severe ovarian hyperstimulation syndrome: a guideline (2023)
Ovarian hyperstimulation syndrome is a serious complication associated with assisted reproductive technology. View the guidelineGuidance for coding limited or follow-up ultrasounds used during an IVF Cycle
I am a coder for a Reproductive Endocrinologist's office and am looking for some guidelines on limited or follow-up ultrasounds used during an IVF Cycle. View the AnswerBilling for cryopreservation procedures on different days
I understand that if cryopreservation of oocytes is performed on two separate dates of service, each date of service was billable. View the AnswerMeasurements to report with ultrasound codes
Are there clear guidelines as to what measurements are required in order to bill for each type of ultrasound? VIew the AnswerBilling IVF lab work
We typically bill our IVF Lab work under the rendering provider who performs the VOR. Who should be the supervising provider for embryology billing? View the AnswerEstradiol Free versus Total
Should patients with fertility issues be billing Estradiol Free (82681) instead of Estradiol Total (82670)? View the AnswerIVF coverage denied for Z31.83 diagnosis code
My wife and I have been seeking IVF treatment and coverage was added for infertility treatment (up to $25,000) but our insurer keeps denying it. View the AnswerCycle coordination fees and 99499, S4042
I reviewed cycle coordination fees, but see that there is no specific code for cycle management. View the AnswerSupervising provider for embryology billing
We typically bill our IVF Lab work under the rendering provider who performs the VOR. Who should be the supervising provider for embryology billing? View the AnswerJournal Club Global - Revisiting the STAR trial: The Fellows debate PGT-A
We are excited to host a debate covering the pros and cons of PGT-A and how new technologies should be validated before clinical implementation. View the VideoInformed consent in assisted reproduction: an Ethics Committee opinion (2023)
Informed consent is a process in which the patient is supported in developing an understanding of medical options. View the Ethics Committee OpinionUnlisted Fertility Treatment CPT Code
Can you please refer me to an unlisted management CPT code for fertility treatment? View the AnswerZ Codes Vs. Procedure Codes For Fertility Preservation Counseling
I am trying to understand better when to use the procreative management code vs the fertility preservation counseling and procedure codes. View the AnswerPregnancy Of Unknown Location
What is the most appropriate ICD-10 code for pregnancy of unknown location (not an ectopic pregnancy)? View the AnswerPregnancy Ultrasound
Our practice does routine ultrasounds (sac check- 76817) at the end of an IVF cycle and bill with a diagnosis code O09.081, pregnancy resulting from ART. View the AnswerIn Vitro Maturation
Have CPT codes been established for maturation in vitro? View the AnswerIUI Same Gender
When managing an IUI or IVF cycle for a female same sex couple or a patient that has no exposure to sperm, what ICD 10 diagnosis should be used? View the AnswerIVF Case Rates
What ICD-10 codes apply to case rates? View the AnswerLimited Monitoring Ultrasound
What is the appropriate code to use for a limited follow-up follicular transvaginal ultrasound? View the AnswerLimited Transvaginal Ultrasound
One of our clients received information that a repeat limited transvaginal ultrasound should be billed with a limited pelvic ultrasound code (76857). View the AnswerMonitoring E&M
Our group would like to know if others are billing an evaluation and management code for ultrasound and blood draw visits? View the AnswerMonitoring FET
What is the correct diagnosis code to use on the follicle ultrasound (76857) for a patient who is undergoing frozen embryo transfer (FET)? View the AnswerMonitoring Ovulation Induction By Nurses
We are considering the use of CPT code 99211 for encounters during cycle management as part of ovulation induction. View the AnswerNon-REI Board Certified MD Performing REI Procedures
My boss has a few follow up questions about a non-REI board certified MD performing REI procedures. View the AnswerEmbryo Storage Fees For Multiple Cycles
We bill embryo storage 89342 for a year's storage. View the AnswerEndometrial Receptivity Analysis
Our physicians are going to start doing an Endometrial Receptivity Analysis. Do you know the appropriate CPT code that should be used?View the Answer
Flat Fee For Outside Monitoring
Can our office charge outside monitoring patients a flat fee to be seen? View the AnswerDiagnosis Code For Same-Sex Egg Donation
We have a same-sex male couple with insurance coverage for IVF. View the AnswerDonor Embryos
Could you give guidance for the correct ICD-10 code(s) to use when a patient is doing an Anonymous Donor Embryo Transfer cycle? View the AnswerCoding For Placement Of A Cervical Stitch
Physicians at our practice are placing a stitch and dilating the cervix after egg retrievals for those patients that have cervical stenosis. View the AnswerBoard Certified Vs. Non-Board Certified Billing
Is coding/billing any different when a non-board certified or non-REI provider submits for REI procedure? View the AnswerAssisted Hatching Billed With Embryo Biopsy
Do you know if both assisted hatching (89253) and embryo biopsy for PGS/PGD/CCS (89290/89291) can be billed during the same cycle? View the AnswerBilling at an Outside Clinic for Lab Services
One of my physicians uses an outside facility to perform the retrievals and transfers. View the AnswerMental-health Services During Assisted Reproduction
A summary of codes for Mental-health Services During Assisted Reproduction compiled by the ASRM Coding Committee. View the Coding SummaryLaboratory Procedures during ART Cycles
A listing of codes, compiled for a fresh ART cycle, transfer, biopsy, cryopreservation of embryos and oocytes, storage, and thawing. View the Coding SummaryJournal Club Global: Evidence for Immunologic Therapies in Women Undergoing ART
Reproductive immunology is perhaps one of the most controversial and promising fields within ART. View the VideoComprehensive guidance for human embryology, andrology, and endocrinology laboratories: management and operations: a committee opinion (2022)
ASRM has published guidance and minimum standards for embryology and andrology laboratories. View the Committee OpinionJournal Club Global - Best Practices of High Performing ART Clinics
This Fertility and Sterility Journal Club Global discusses February’s seminal article, “Common practices among consistently high-performing in vitro fertilization programs in the United States: a 10 year update.” View the VideoJournal Club Global - Fertilization rate as a novel indicator in ART results
This Journal Club Global discusses a provocative article recently published in Fertility and Sterility, discussing the results of a multicenter retrospective cohort study with the objective to appraise the fertilization rate as a predictive factor for cumulative live birth rate (CLBR). View the VideoJournal Club Global - Are We Approaching Automation in ART?
Some ART diagnostic devices are already available and offer objective tools of evaluation. View the VideoGuidance on the limits to the number of embryos to transfer: a committee opinion (2021)
ASRM's guidelines for the limits on the number of embryos to be transferred during IVF cycles have been further refined ... View the Committee OpinionRole of tubal surgery in the era of assisted reproductive technology: a committee opinion (2021)
This document reviews surgical options for reparative tubal surgery and the factors that must be considered when deciding between surgical repair and IVF.View the Committee Opinion
Minimum standards for practices offering assisted reproductive technologies: a committee opinion (2021)
A framework for assisted reproductive technology (ART) programs that meet or exceed the requirements suggested by the Centers for Disease Control View the Committee OpinionJournal Club Global - Recurrent Implantation Failures in ART: Myth or Reality?
The role of immunotherapy in in vitro fertilization: a guideline (2018)
ASRM guideline evaluates current evidence on immunotherapy use in IVF, finding limited support for routine adjuvant immunomodulating treatments. View the Committee OpinionThe International Glossary on Infertility and Fertility Care, 2017†‡§ (2017)
A globally‑consensus glossary of 283 infertility and fertility‑care terms developed in 2017 to harmonize communication across clinicians, researchers & patients. View the Committee Joint GuidelineCorrect coding for laboratory procedures during assisted reproductive technology cycles (2016)
This document provides updated coding information for services related to assisted reproductive technology procedures. View the Coding Committee DocumentRecommended practices for the management of embryology, andrology, and endocrinology laboratories: a committee opinion (2014)
A general overview for good management practices within the endocrinology, andrology, and embryology laboratories in the United States. View the RecommendationBest practices of ASRM and ESHRE: a journey through reproductive medicine (2012)
ASRM and ESHRE are the two largest societies in the world whose members comprise the major experts and professionals working in reproductive medicine. View the Committee Joint GuidelineTopic Resources
Fertility and Sterility On Air - TOC: February 2026
FNS On Air reviews Fertility and Sterility Feb 2026 issue, covering AMH, PGTA, AI embryo selection, IVF outcomes, and key clinical controversies in today's insights. Listen to the EpisodeTransfer of embryos affected by monogenic conditions: an Ethics Committee Opinion (2025)
Patient requests to transfer embryos with serious monogenic disorders detected in preimplantation testing are rare; this opinion discusses physician responses. View the Committee OpinionDisclosure of medical errors and untoward events involving gametes and embryos: an Ethics Committee opinion (2024)
Medical providers have an ethical duty to disclose clinically significant errors involving gametes and embryos. View the Committee OpinionHow to bill for an FET
Is there a new update to the 89272 code that allows its use without View the AnswerCodes for Embryo Biopsy
When doing a preimplantation genetic test (PGT) biopsy, can you bill for each day a biopsy is performed or can you only bill once for the cycle? View the AnswerBilling for assisted hatching at biopsy and transfer
We would also like to know if you can bill assisted hatching with biopsy and then assisted hatching again during the transfer cycle. View the AnswerShipping of frozen embryos
I have some infertility coverage, under which my insurance said they will cover frozen embryo shipping/transport from one facility to another. View the AnswerClinical management of mosaic results from preimplantation genetic testing for aneuploidy of blastocysts: a committee opinion (2023)
This document incorporates studies about mosaic embryo transfer and provides evidence-based considerations for embryos with mosaic results on PGT-A. View the Committee OpinionHow to EDGE
Explore the ASRM EDGE tool for embryo grading. Learn grading steps, view dashboards, and assign blastocyst grades using the SART and Gardner scales in ASRM Academy. View the ASRMed Talk VideoJournal Club Global: Transferencia de embriones frescos versus congelados: ¿Cuál es la mejor opción
Los resultados de nuevas técnicas de investigación clínica que utilizan información de bancos nacionales de vigilancia médica. View the VideoDefining embryo donation: an Ethics Committee opinion (2023)
Does the number of eggs being frozen matter?
There is currently only one CPT code for the cryopreservation of mature oocytes and embryos. View the AnswerReproductive Tissue Storage
What are the CPT codes for the Storage of Reproductive Cells/Tissues? View the AnswerICSI and Embryo Biopsy
How to bill for ICSI or embryo biopsies that occur in different days? View the AnswerLab RVUs
Is there a list of RVUs for embryology and andrology laboratory procedures, and if so, where can it be found? View the AnswerEmbryo Biopsy
Have any new codes been introduced for the lab portion of PGT? View the AnswerEmbryo Biopsy Embryologist Travel Costs
Can we bill insurance for the biopsy procedure? Can we bill for travel expenses? View the AnswerEmbryo Biopsy PGS Testing
What codes are appropriate for PGS testing? View the AnswerEmbryo Co-culture
Can codes 89250 and 89251 be billed on different days of the same cycle? View the AnswerEmbryo Culture Denied As Experimental
We have received denials from insurance payers when billing CPT code 89251. View the AnswerEmbryo Culture Less Than And More Than Four Days
When coding 89250 culture of oocytes/embryo <4 days, should that code be submitted to the insurance company for each of the days? View the AnswerEmbryo Freezing/Thawing
Our question refers to the CPT code 89258 “Cryopreservation; Embryo(s)” and 89352 “Thawing of Cryopreserved; Embryo”. View the AnswerEmbryo Storage Fees For Multiple Cycles
We bill embryo storage 89342 for a year's storage. View the AnswerEmbryo Thawing/Warming
Is it allowable to bill 89250 for the culture of embryos after thaw for a frozen embryo transfer (FET) cycle? View the AnswerGamete Thawing/Warming
Can patients be charged for each vial/straw of reproductive gametes or tissues thawed? View the AnswerD&C Under Ultrasound Guidance
What are the CPT codes and ICD-10 codes for coding a surgical case for a patient with history of Stage B adenocarcinoma of the cervix ... View the AnswerAssisted Hatching Billed With Embryo Biopsy
Do you know if both assisted hatching (89253) and embryo biopsy for PGS/PGD/CCS (89290/89291) can be billed during the same cycle? View the AnswerAssisted Zona Hatching
Can assisted hatching and embryo biopsy for PGT-A; PGT-M or PGT-SR be billed during the same cycle? View the AnswerBilling For Cryopreservation Of Embryos Under The Male Partner
Can 89258 be billed under the male partner of a female patient? View the AnswerEmbryo Transfer
A summary of Embryo Transfer codes collected by the ASRM Coding Committee View the Coding SummaryJournal Club Global: Is PGT-P cutting edge or should we cut it out?
PGT for polygenic risk scoring (PGT-P) is a novel screening strategy of embryos for polygenic conditions and traits. View the VideoDisposition of unclaimed embryos: an Ethics Committee opinion (2021)
Programs should create and enforce written policies addressing the designation, retention, and disposal of unclaimed embryos. View the Committee OpinionA review of best practices of rapid-cooling vitrification for oocytes and embryos: a committee opinion (2021)
The focus of this paper is to review best practices for rapid-cooling cryopreservation of oocytes and embryos. View the Committee OpinionEthics in embryo research: a position statement by the ASRM Ethics in Embryo Research Task Force and the ASRM Ethics Committee (2020)
Scientific research using human embryos advances human health and offspring well-being and provides vital insights into the mechanisms for reproduction. View the Committee OpinionGuidance for Providers Caring for Women and Men Of Reproductive Age with Possible Zika Virus Exposure (Updated 2019)
This ASRM guidance specifically addresses Zika virus infection issues and concerns of individuals undergoing assisted reproductive technologies (ART). View the GuidelineBlastocyst culture and transfer in clinically assisted reproduction: a committee opinion (2018)
The purposes of this document is to review the literature regarding the clinical application of blastocyst transfer. View the Committee OpinionPosthumous retrieval and use of gametes or embryos: an Ethics Committee opinion (2018)
Posthumous gamete retrieval or use is ethically justifiable if written documentation from the deceased authorizing the procedure is available. View the Committee OpinionRecommended practices for the management of embryology, andrology, and endocrinology laboratories: a committee opinion (2014)
A general overview for good management practices within the endocrinology, andrology, and embryology laboratories in the United States. View the RecommendationASRM EDGE Tool
Get the EDGE on your fellow Embryologists! As the grading of embryos varies within IVF laboratories and between laboratories, EDGE allows you to compare yourself against embryologists in the US and around the world. Learn more about the EDGE ToolTopic Resources
Journal Club Global: Healthy euploid dizygotic twin birth after transfer of nonmosaic aneuploid embryos
This interactive session will feature an in-depth discussion on the paper “Healthy euploid dizygotic twin birth after transfer of nonmosaic aneuploid embryos.”
View the Video