Embryo Biopsy Code 89290
Embryo biopsies are often done over several dates of service in a single cycle. Is the 89290(1) meant to be coded once for the total number of biopsies done in a single cycle, or is it meant to be coded each date of service it is done throughout the cycle?
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Coding Q&A
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Billing for Ultrasounds and Labs
When billing for ultrasounds and labs, is it necessary
Use of Code 99211 for a Monitoring Appointment
Is it appropriate to use code 99211 if a patient is scheduled for a monitoring visit
Appropriate Use of Modifier -25
Is Modifier -25 appropriate in the monitoring cycle when an ultrasoundCoding Corner
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ReproductiveFacts.org provides a wide range of information related to reproductive health and infertility through patient education fact sheets, infographics, videos, and other resources.
Topic Resources
View more on the topic of embryo
Fertility and Sterility On Air - TOC: March 2026
Explore the March 2026 Fertility and Sterility On Air episode covering exercise during FET cycles, metabolic health, IVF triggers, PGT insights, and ectopic pregnancy research. Listen to the Episode
Fertility and Sterility On Air - TOC: February 2026
FNS On Air reviews Fertility and Sterility Feb 2026 issue, covering AMH, PGTA, AI embryo selection, IVF outcomes, and key clinical controversies in today's insights. Listen to the Episode
Journal Club Global en Español: AMMR 2025
Experts discuss chaotic embryo classification, PGT-A rebiopsy outcomes, embryo quality, biopsy techniques, and transfer protocols for mosaic embryos. View the Video
Transfer of embryos affected by monogenic conditions: an Ethics Committee Opinion (2025)
Patient requests to transfer embryos with serious monogenic disorders detected in preimplantation testing are rare; this opinion discusses physician responses. View the Committee Opinion
Disclosure of medical errors and untoward events involving gametes and embryos: an Ethics Committee opinion (2024)
Medical providers have an ethical duty to disclose clinically significant errors involving gametes and embryos. View the Committee Opinion
How to bill for an FET
Is there a new update to the 89272 code that allows its use without View the Answer
Codes for Embryo Biopsy
When doing a preimplantation genetic test (PGT) biopsy, can you bill for each day a biopsy is performed or can you only bill once for the cycle? View the Answer
Billing for assisted hatching at biopsy and transfer
We would also like to know if you can bill assisted hatching with biopsy and then assisted hatching again during the transfer cycle. View the Answer
Shipping of frozen embryos
I have some infertility coverage, under which my insurance said they will cover frozen embryo shipping/transport from one facility to another. View the Answer
Clinical management of mosaic results from preimplantation genetic testing for aneuploidy of blastocysts: a committee opinion (2023)
This document incorporates studies about mosaic embryo transfer and provides evidence-based considerations for embryos with mosaic results on PGT-A. View the Committee Opinion
How to EDGE
Explore the ASRM EDGE tool for embryo grading. Learn grading steps, view dashboards, and assign blastocyst grades using the SART and Gardner scales in ASRM Academy. View the ASRMed Talk Video
Journal Club Global: Transferencia de embriones frescos versus congelados: ¿Cuál es la mejor opción
Los resultados de nuevas técnicas de investigación clínica que utilizan información de bancos nacionales de vigilancia médica. View the Video
Defining embryo donation: an Ethics Committee opinion (2023)
The ethical appropriateness of patients donating embryos to other patients for family building, or for research, is well established.
View the Committee Opinion
ASRM Position Statement on Personhood Measures
The American Society for Reproductive Medicine (ASRM) is strongly opposed to measures granting constitutional rights or protections and “personhood” status to fertilized reproductive tissues.
Does the number of eggs being frozen matter?
There is currently only one CPT code for the cryopreservation of mature oocytes and embryos. View the Answer
Reproductive Tissue Storage
What are the CPT codes for the Storage of Reproductive Cells/Tissues? View the Answer
ICSI and Embryo Biopsy
How to bill for ICSI or embryo biopsies that occur in different days? View the Answer
Lab RVUs
Is there a list of RVUs for embryology and andrology laboratory procedures, and if so, where can it be found? View the Answer
Embryo Storage Fees For Multiple Cycles
We bill embryo storage 89342 for a year's storage. View the Answer
Embryo Biopsy
Have any new codes been introduced for the lab portion of PGT? View the Answer
Embryo Biopsy Embryologist Travel Costs
Can we bill insurance for the biopsy procedure? Can we bill for travel expenses? View the Answer
Embryo Biopsy PGS Testing
What codes are appropriate for PGS testing? View the Answer
Embryo Co-culture
Can codes 89250 and 89251 be billed on different days of the same cycle? View the Answer
Embryo Culture Denied As Experimental
We have received denials from insurance payers when billing CPT code 89251. View the Answer
Embryo Culture Less Than And More Than Four Days
When coding 89250 culture of oocytes/embryo <4 days, should that code be submitted to the insurance company for each of the days? View the Answer
Embryo Freezing/Thawing
Our question refers to the CPT code 89258 “Cryopreservation; Embryo(s)” and 89352 “Thawing of Cryopreserved; Embryo”. View the Answer
Embryo Thawing/Warming
Is it allowable to bill 89250 for the culture of embryos after thaw for a frozen embryo transfer (FET) cycle? View the Answer
Gamete Thawing/Warming
Can patients be charged for each vial/straw of reproductive gametes or tissues thawed? View the Answer
D&C Under Ultrasound Guidance
What are the CPT codes and ICD-10 codes for coding a surgical case for a patient with history of Stage B adenocarcinoma of the cervix ... View the Answer
Assisted Hatching Billed With Embryo Biopsy
Do you know if both assisted hatching (89253) and embryo biopsy for PGS/PGD/CCS (89290/89291) can be billed during the same cycle? View the Answer
Assisted Zona Hatching
Can assisted hatching and embryo biopsy for PGT-A; PGT-M or PGT-SR be billed during the same cycle? View the Answer
Billing For Cryopreservation Of Embryos Under The Male Partner
Can 89258 be billed under the male partner of a female patient? View the Answer
Embryo Transfer
A summary of Embryo Transfer codes collected by the ASRM Coding Committee View the Coding Summary
Journal Club Global: Is PGT-P cutting edge or should we cut it out?
PGT for polygenic risk scoring (PGT-P) is a novel screening strategy of embryos for polygenic conditions and traits. View the Video
Disposition of unclaimed embryos: an Ethics Committee opinion (2021)
Programs should create and enforce written policies addressing the designation, retention, and disposal of unclaimed embryos. View the Committee Opinion
A review of best practices of rapid-cooling vitrification for oocytes and embryos: a committee opinion (2021)
The focus of this paper is to review best practices for rapid-cooling cryopreservation of oocytes and embryos. View the Committee Opinion
Ethics in embryo research: a position statement by the ASRM Ethics in Embryo Research Task Force and the ASRM Ethics Committee (2020)
Scientific research using human embryos advances human health and offspring well-being and provides vital insights into the mechanisms for reproduction. View the Committee Opinion
Guidance for Providers Caring for Women and Men Of Reproductive Age with Possible Zika Virus Exposure (Updated 2019)
This ASRM guidance specifically addresses Zika virus infection issues and concerns of individuals undergoing assisted reproductive technologies (ART). View the Guideline
Blastocyst culture and transfer in clinically assisted reproduction: a committee opinion (2018)
The purposes of this document is to review the literature regarding the clinical application of blastocyst transfer. View the Committee Opinion
Posthumous retrieval and use of gametes or embryos: an Ethics Committee opinion (2018)
Posthumous gamete retrieval or use is ethically justifiable if written documentation from the deceased authorizing the procedure is available. View the Committee Opinion
Recommended practices for the management of embryology, andrology, and endocrinology laboratories: a committee opinion (2014)
A general overview for good management practices within the endocrinology, andrology, and embryology laboratories in the United States. View the Recommendation
