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Exploring Fertility Preservation In Children Suffering From Other Disease

October 15 , 2013
by: ASRM Office of Public Affairs
Published in ASRM Press Release

HIGHLIGHTS FROM THE INTERNATIONAL FEDERATION OF FERTILITY SOCIETIES 21st WORLD CONGRESS ON FERTILITY AND STERILITY AND THE 69th ANNUAL MEETING OF THE AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE

Boston, MA – Researchers at the International Federation for Fertility Societies/American Society for Reproductive Medicine meeting today presented work investigating options for preserving the fertility of children with diseases including cancers.  A common side effect of some cancer treatments is impaired fertility. In adult patients, collection and freezing of sperm or eggs is becoming increasing utilized, however, such treatments in children has been more challenging. These new studies show significant improvements in offering such treatments to both boys and girls.

An Israeli team presented research examining a new technique designed to allow the growth and maturation of testicular cultures taken from pre-pubertal boys prior to their chemotherapy for cancer. The scientists extracted testicular germ cells via biopsy and used a ground breaking three dimensional cell culturing technique to grow the cells in the laboratory. Growth and differentiation of the cells has been good and they are currently being evaluated for signs of sperm development.

A team in New York reported on the feasibility of using ovarian stimulation and oocyte cryopreservation in post pubertal girls. They reported a series of case studies in girls aged 13-15 who suffered from Turner’s syndrome, tumors or leukemia. They found using somewhat different drug protocols than used with adults, that ovarian stimulation, retrieval and freezing techniques could be used to preserve the fertility of girls at risk of losing their fertility.

“Fertility preservation for adults is becoming standard of care for cancer patients, however we still have to work to do in order for us to be able to offer fertility preservation to children and adolescents. This important research moves us closer to that goal,” stated Richard Reindollar MD, President-elect of ASRM.

O-207 Fertility Preservation of Pre-Pubertal Cancer Patient Boys Before Aggressive Chemotherapy: Preliminary Results form In Vitro Culture of Fresh Testicular Tissue from 3 Pre-Pubertal Patients.
M Huleihel et al
 

O-208 Feasibility of Ovarian Stimulation and Oocyte Cryopreservation for Fertility Preservation in Female Children
G. Bedoschi et al
 

Representing more than 50 fertility societies from around the globe, the International Federation of Fertility Societies (IFFS) is the world’s principal international fertility organization. The IFFS was founded in 1951, and held its first congress in New York in 1953. The IFFS mission is to stimulate basic and clinical research, disseminate education and encourage superior clinical care of patients in infertility and reproductive medicine. Website: http://www.iffs-reproduction.org/ 

The American Society for Reproductive Medicine, founded in 1944, is an organization of more than 7,000 physicians, researchers, nurses, technicians and other professionals dedicated to advancing knowledge and expertise in reproductive biology.  Affiliated societies include the Society for Assisted Reproductive Technology, the Society for Male Reproduction and Urology, the Society for Reproductive Endocrinology and Infertility, the Society of Reproductive Surgeons and the Society of Reproductive Biologists and Technologists.


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