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View Our Top Three #ASRM2020 Plenaries - NOW FREE!

We are sharing our top three most viewed plenary sessions from the ASRM 2020 Scientific Congress--here and now, for free!

To view more of #ASRM2020, visit www.asrmcongress.org and register or log in for on-demand content through December 31, 2020.

Far sooner than most of us realize, the genetics revolution will transform the world within and around us. But while we today think about genetic technologies primarily in the context of health care, the tools we are developing will soon be changing the way we make babies, the nature of the babies we make, and ultimately our evolutionary trajectory as a species. 

The Camran Nezhat, MD Lectureship in Innovations in Medicine: Non-Invasive Preimplantation Genetic Testing for Aneuploidy, Monogenic and Multigenic Diseases, presented by Dr. Xiaoliang Sunney Xie, Peking University, Bejng, China.
Preimplantation genetic testing for aneuploidy (PGT-A) with trophectoderm (TE) biopsy is widely applied in in vitro fertilization to identify aneuploid embryos. However, potential safety concerns regarding biopsy and restrictions to only those embryos suitable for biopsy pose limitations. In addition, embryo mosaicism gives rise to false positives and false negatives in PGT-A because the inner cell mass (ICM) cells, which give rise to the fetus, are not tested. We report a noninvasive preimplantation genetic testing for aneuploidy (niPGT-A) in the spent culture media by measuring the copy numbers of cell-free DNA from the ICM only. We also have demonstrated niPGT-A in the spent culture for monogenic and polygenic diseases by high-precision detection of point mutations in the cell free deoxyribonucleic acid (DNA) through linkage analyses.

Special Lecture: Andy & Sofia, presented by Andres Trevino, Patient Advocate, Massachusetts.
A synopsis from the book written by the speaker, Andres Trevino, Andy & Sofia – Stem Cells, Scientific Miracles and One Fit Savior. In an incubated petri dish in a Boston laboratory, a cluster of eight living cells holds the key to a daring new era of medical science. These cells come from a human embryo containing genetic material from my wife Paulina and me, obtained through in vitro fertilization (IVF). Research using these cells holds enormous potential to cure a fatal disease, saving the lives of countless children and relieving their families of unspeakable pain. We lived that pain ourselves. When our son was born, we did not know what a tortuous road stretched ahead of us–how our baby would suffer, and how we would suffer with him.

To view all three plenaries, click here.


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