Journal Club Global: The Association of Ovarian Reserve and Embryo Aneuploidy
Date: November 07, 2023
Author: Fertility and Sterility
Recent research suggests that the Antimullerian hormone (AMH) may not reliably predict embryo health in both infertility and non-infertility cases. Diminished ovarian reserve doesn't seem to significantly impact embryo quality or live birth rates compared to normal ovarian reserve; however, there is some evidence of a link between lower ovarian reserve and fewer healthy embryos, independent of age. This connection between egg quality and quantity may be influenced by factors like DNA repair, mitochondrial function, and genetic changes over time. Variations in research methods and patient selection can explain differences in study results. Fertility is not solely about egg quantity; egg quality plays a crucial role, and our understanding of this connection is evolving in reproductive science.