Video
Journal Club Global: Cost effectiveness analyses of PGT-A
The upcoming Journal Club Global will explore a provocative article on the cost effectiveness of PGT-A recently published in Fertility and Sterility. The article provides a systematic literature review of 22 published studies and summarizes the current cost effectiveness evidence on this topic. Infertility treatments are notoriously expensive and often not covered by insurance. PGT is expensive and the clinical efficacy varies in the existing published trials, at least in part due to heterogeneity in study design. Therefore, studying the cost-effectiveness of PGT is a challenging research question which we will explore.
View the Article being discussed: Cost-effectiveness analyses of preimplantation genetic testing
Questions to be addressed:
- What are the key steps to cost effectiveness analyses?
- What are the challenges in assessing cost effectiveness in general and specific to PGT-A?
- How should heterogenous studies be assessed and synthesized systematically?
- What are the main factors driving heterogeneity in the cost effectiveness of PGT-A?
Panelists:
Mina Popovic PhD
Kate Devine MD
Chaim Jalas PhD
Richard Scott, MD HCLD
Diego Marin PhD
Kristine McWilliams MD PhD HCLD
Moderators:
Paul Pirtea, M.D.
Dominique de Ziegler, MD.
Micah J. Hill, DO
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Fertility and Sterility
F&S Reports
F&S Reports is an open-access journal that publishes peer-reviewed original scientific articles in clinical and translational research that have strong potential to transform clinical practice.
F&S Reviews
F&S Reviews publishes both systematic and comprehensive, authoritative review articles spanning reproductive medicine or science.
F&S Science
F&S Science publishes peer-reviewed original scientific articles in basic, laboratory, and translational research that has strong potential to transform clinical practice.
Fertility and Sterility
Fertility and Sterility® is an international journal for health professionals who treat and investigate problems of infertility and human reproductive disorders.
Journal Club Global
Fertility and Sterility Journal Club Global is an interactive online discussion of a hot topic or seminal article from Fertility and Sterility.
Topic Resources
Fertility and Sterility On Air - TOC: Dec 2024
Podcast episode discussing reproductive medicine highlights, including ASRM 2024 insights, meta-analysis integrity, donor ethics, and IVF communication challenges. Listen to the Episode
Fertility and Sterility On Air - TOC: November 2024
Explore insights on the latest Fertility and Sterility On Air podcast, discussing ART workups, LGBTQ family building, genetic screening, and original research. Listen to the Episode
Fertility and Sterility On Air - Unplugged: December 2024
Explore the complexities of chromosomal abnormalities in embryos, their impact on fertility, and counseling strategies for patients in this in-depth podcast discussion. Listen to the Episode
Journal Club Global: Embriões mosaicos ao Teste Genético Pré-Implantacional para Aneuploidia (PGT-A): o que fazer?
Discutiremos embriões mosaicos ao teste genético pré-implantacional para aneuploidia (PGT-A) View the Video
Journal Global Club From TSRM 2024: Preimplantation genetic testing for aneuploidy in unexplained recurrent pregnancy loss: A systematic review and meta-analysis
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Caitlin Hebert discusses fertility counseling, the importance of carrier screening, and overcoming barriers for patients while highlighting the role of genetic counseling. View the ASRMed Talk Video
Use of preimplantation genetic testing for monogenic adult-onset conditions: an Ethics Committee opinion (2024)
Preimplantation genetic testing for adult-onset monogenic diseases is ethically allowed when fully penetrant or conferring disease predisposition. View the Committee Opinion
Codes for Embryo Biopsy
When doing a preimplantation genetic test (PGT) biopsy, can you bill for each day a biopsy is performed or can you only bill once for the cycle? View the Answer
Fertility and Sterility On Air - Live from ESHRE 2024: Part 2
Explore fresh embryo transfers, progesterone elevation, and day-seven embryo utility from experts at ESHRE 2024. Cutting-edge fertility insights await! Listen to the Episode
The use of preimplantation genetic testing for aneuploidy: a committee opinion (2024)
PGT-A use in the U.S. is rising, but its value as a routine IVF screening test is unclear, with mixed results from various studies. View the Committee Opinion
Fertility and Sterility On Air - TOC: July 2024
Articles this month include: predicting ART complications, laser assisted hatching on vitrified blastocysts, predictive models of miscarriage and more.Listen to the Episode
Journal Club Global: Recent clinical trials in Fertility and Sterility from the Asia Pacific region
Join ASPIRE 2024 for a Journal Club Global on PGT-A and IVF. Learn from top experts discussing recent clinical trial data and pregnancy outcomes View the Video
Coding for an endometrial biopsy/Mock cycle
We had patients request us to bill their insurance for the two monitoring visits and the Endo BX and change the diagnosis code to something that is payable. View the Answer
Coding PGT requisitions to the PGT lab
Do you have any recommended codes to use for PGT requisitions to the PGT lab? View the Answer
Genetics: Is Expanded Carrier Screening the Standard of Care?
Hannah Green, a genetic counselor at NYU, discusses the benefits and limitations of expanded carrier screening, highlighting its impact on clinical practice and patient care. View the ASRMed Talk Video
Genetics - Extra Testing, Passthrough or Money Maker?
Danielle Soltesz of RMA New York discusses the complex economics and ethical considerations of genetic testing in reproductive medicine, exploring costs, patient care, and sustainability. View the ASRMed Talk Video
Clinical management of mosaic results from preimplantation genetic testing for aneuploidy of blastocysts: a committee opinion (2023)
This document incorporates studies about mosaic embryo transfer and provides evidence-based considerations for embryos with mosaic results on PGT-A. View the Committee Opinion
Journal Club Global - Revisiting the STAR trial: The Fellows debate PGT-A
We are excited to host a debate covering the pros and cons of PGT-A and how new technologies should be validated before clinical implementation. View the Video
Results Review
What CPT code is most appropriate to submit for Physician Time to review CCS/PGS/PGD results? View the Answer
Sperm DNA Fragmentation
Is there a CPT code for HALO DNA Fragmentation for sperm? View the Answer
ICSI and Embryo Biopsy
How to bill for ICSI or embryo biopsies that occur in different days? View the Answer
Embryo Biopsy
Have any new codes been introduced for the lab portion of PGT? View the Answer
Embryo Biopsy Embryologist Travel Costs
Can we bill insurance for the biopsy procedure? Can we bill for travel expenses? View the Answer
Embryo Biopsy PGS Testing
What codes are appropriate for PGS testing? View the Answer
Genetic Counseling
Does ASRM have any guidance for how to bill for genetic counseling services provided by a genetic counselor?View the Answer
Assisted Zona Hatching
Can assisted hatching and embryo biopsy for PGT-A; PGT-M or PGT-SR be billed during the same cycle? View the Answer
Indications and management of preimplantation genetic testing for monogenic conditions: a committee opinion (2023)
ASRM has updated its opinion on PGT for monogenic conditions, providing guidance on clinical and technical complexities. View the Committee Opinion
Journal Club Global - PGT-A - Can non-invasive approaches based on spent medium analysis
PGT-A by trophectoderm biopsy aims to select available euploid embryos for transfer. View the Video
ASRM müllerian anomalies classification 2021
The Task Force set goals for a new classification and chose to base it on the iconic AFS classification from 1988 because of its simplicity and recognizability. View the Committee Opinion
Journal Club Global - Accuracy of Preimplantation Genetic Testing for Aneuploidies
Reproductive and hormonal considerations in women at increased risk for hereditary gynecologic cancers: Society of Gynecologic Oncology and American Society for Reproductive Medicine Evidence-Based Review (2019)
Providers who care for women at risk for hereditary gynecologic cancers must consider the impact of these conditions. View the Joint Statement
Disclosure of sex when incidentally revealed as part of preimplantation genetic testing (PGT): an Ethics Committee opinion (2018)
Clinics may develop a policy to disallow selecting which embryos to transfer based on sex and choose to use only embryo quality as selection criteria. View the Committee Opinion
Transferring embryos with genetic anomalies detected in preimplantation testing: an Ethics Committee Opinion (2018)
Patient requests for transfer of embryos with genetic anomalies linked to serious health-affecting disorders detected in preimplantation testing are rare but do exist. View the Committee Document
Best practices of ASRM and ESHRE: a journey through reproductive medicine (2012)
ASRM and ESHRE are the two largest societies in the world whose members comprise the major experts and professionals working in reproductive medicine. View the Committee Joint Guideline
