Interactive Session - Aggressive or Delayed Management of the Klinefelter Adolescent: What Do the Data Show? An Interactive Debate

Date:October 21, 2014

Time:1:15 pm - 2:15 pm

Location:HCC312 - Hawaii Convention Center


Peter N. Schlegel, M.D. (Chair), Weill Cornell Medical College

Darius A. Paduch, M.D., Weill Cornell Medical College

Robert D. Oates, M.D., Boston Medical Center


Needs Assessment and Description
This interactive session for clinicians and researchers involved in male fertility care will provide expert review of the potential for early treatment of Klinefelter syndrome in adolescents to improve future fertility as well as the potential developmental benefits of androgen therapy. Results of early intervention with hormonal therapy and sperm retrieval will be presented. The risks and results of such treatment of adult males with Klinefelter syndrome will be discussed, and the limitations of current published literature will be reviewed in an interactive format with audience participation. 

Learning Objectives
At the conclusion of this session, participants should be able to: 

  1. Discuss results of early vs. late fertility treatment for males with Klinefelter syndrome. 
  2. Identify developmental issues that can be affected by androgen therapy in the Klinefelter male. 
ACGME Competency
Patient Care 

In a 28-year-old male with Klinefelter syndrome, aromatase inhibitor therapy is most likely to:
a. Increase estradiol.
b. Decrease FSH.
c. Increase testosterone.
d. Improve sperm retrieval rates.


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