Afternoon Symposium - What Comes After the Big Chill: The Metabolic and Clinical Consequences of Oocyte and Ovarian Tissue Cryopreservation
Date:October 22,
2012
Time:4:15 pm - 6:15 pm
Location:Ballroom 6 - San Diego Convention Center
Presenters
David F. Albertini, Ph.D. (Chair), University of Kansas Medical Center
S. Samuel Kim, M.D., University of Kansas Medical Center
Tommaso Falcone, M.D., Cleveland Clinic
Evelyn Flaherty-Brown, Ph.D., The University of Edinburgh
What Comes After the Big Chill: The Metabolic and Clinical Consequences of Oocyte and Ovarian Tissue Cryopreservation - A Look to the Future
Needs Assessment and Description
As oocyte and ovarian tissue cryopreservation gain
widespread usage in the field of human assisted
reproductive technology (ART), the need to validate and
improve the safety and efficacy of these procedures
is paramount to future applications. Few efforts have
been made to document the short-term consequences
of thawing, transplantation or subsequent culturing of
ovarian cortical strips, especially with respect to metabolic
properties of follicles. The goal of this live course is to inform
clinicians and scientists of recent methodological and
outcome measures that are being used to evaluate the
integrity and developmental potential of oocytes and
tissues subjected to cryopreservation.
Learning Objectives
At the conclusion of this session, participants should be able
to:
- Review current protocols adopted for cryopreservation
and thawing of human oocytes and ovarian tissues and
summarize their utility in human ARTs.
- Discuss the link between sample thawing and the
recovery of metabolic function in the context of embryo
transfer and tissue transplantation.
ACGME Competency
Medical Knowledge
TEST QUESTION:
Thawing of ovarian tissues with subsequent culture or
transplantation is likely to result in which of the following:
- Widespread apoptosis of somatic ovarian cell types
- Widespread apoptosis of oocytes
- Activation of cell survival pathways
- Tissue necrosis