Needs Assessment and Description
The epididymis plays a crucial role in the establishment of male fertility. Infertility is often caused by sperm that have low motility and interact poorly with the oocyte. Spermatozoa acquire these functions mainly in the epididymis. This live course for andrologists, laboratory scientists and other healthcare professionals will discuss how epithelial cells that line the epididymal lumen work in a concerted manner to generate and maintain a unique environment that is conducive to the maturation and survival of spermatozoa.

Learning Objectives 
At the conclusion of this presentation, participants should be able to:

1. Discuss the role of the epididymis in male fertility and the impact of sperm with low motility on fertility. 
2. Describe the mechanism by which epididymal epithelial cells generate and maintain a unique environment that is conducive to the maturation and survival of spermatozoa.

ACGME Competency
Medical Knowledge

TEST QUESTION:
The epididymis is the long coiled tube that connects the testes to the vas deferens. What is the role of the epididymis?

1. Produces testosterone
2. Secretes inhibin and activin, which regulate follicle stimulating hormone (FSH) secretion
3. Provides a luminal environment for the process of spermiation
4. Provides a luminal environment for the process of spermatogenesis 
5. Provides a luminal environment that is essential for the maturation of sperm